The Surprising Link: Endometriosis, Yeast Infections, and BV

October 31, 2025

If you have endometriosis, you’re likely focused on managing common symptoms like pelvic pain and heavy bleeding. But what if those recurrent, frustrating yeast infections or bouts of bacterial vaginosis (BV) you’ve been experiencing are also connected? A growing body of scientific research shows a significant link between endometriosis and the health of your vaginal microbiome.

At ESSI, we believe in looking at the whole picture. Understanding this connection is a crucial part of a comprehensive, patient-centric approach to care.

A Delicate Balance: Your Vaginal Microbiome

First, let’s talk about the vaginal microbiome. A healthy vagina is home to a community of microorganisms, dominated by beneficial bacteria called Lactobacillus. These “good” bacteria produce lactic acid, creating an acidic environment that naturally protects you from infections.

When this delicate balance is thrown off—a state called dysbiosis—the number of protective Lactobacillus decreases. This allows harmful bacteria or yeast to overgrow, leading to conditions like BV or yeast infections. Studies are now showing that women with endometriosis often have this kind of microbial imbalance.

The Link Between Endometriosis and BV

Researchers have found a strong correlation between endometriosis and the types of bacteria that cause bacterial vaginosis. The leading theory is called the “bacterial contamination hypothesis.”

It suggests that during retrograde menstruation (when menstrual blood flows back into the pelvis), a vaginal microbiome imbalanced with BV-associated bacteria can transport these microbes into the pelvic cavity. These harmful bacteria can trigger a chronic inflammatory immune response, which is the exact type of environment where endometriosis lesions thrive and grow.

The Link Between Endometriosis and Yeast Infections

The connection to yeast infections (usually caused by Candida) is also becoming clearer, likely stemming from a few key factors:

  • Chronic Inflammation: Endometriosis creates a state of constant inflammation throughout the body. This inflammatory environment can make you more susceptible to yeast overgrowth.
  • Hormonal Influence: Estrogen can promote the growth of both endometrial tissue and Candida. Since many endometriosis patients experience estrogen dominance, this can create a perfect storm for both conditions to flare up.
  • Immune Dysfunction: Endometriosis is known to be associated with a dysregulated immune system. A compromised immune response can make it harder for your body to keep naturally occurring yeast in check, leading to recurrent infections.

What This Means for Your Endometriosis Care

While we’re still learning if the imbalance contributes to causing endometriosis or if endometriosis creates the imbalance, the association is undeniable.

This research validates the experiences of so many patients who feel their bodies are fighting battles on multiple fronts. It confirms that your recurrent vaginal infections aren’t just a separate, unrelated issue. They may be a piece of the larger endometriosis puzzle.

If you’re struggling with both endometriosis and recurrent BV or yeast infections, it’s vital to discuss it with your specialist. At ESSI, we understand these complex interactions. Addressing your vaginal health may be an important component of managing your overall inflammatory symptoms and improving your quality of life.

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