Dr. Marcello Ceccaroni: Profile of a Surgical Innovator

November 21, 2025

A Profile in Surgical Innovation: Why ESSI is Honored to Have Dr. Marcello Ceccaroni on Our Team

In the world of medicine, there are skilled surgeons, and then there are “Original Innovators”—the rare individuals who don’t just practice medicine but fundamentally change its direction. It is with immense pride that we at Endometriosis Surgical Specialists International (ESSI) count one of these true pioneers as a core member of our global team: Dr. Marcello Ceccaroni (Learn more about ISSA).

While his name is legendary in his home country of Italy, where the press has placed him in the “Olympus” of top physicians, his impact is truly global. We want to provide a clear profile in English of why Dr. Ceccaroni is one of the most important figures in modern endometriosis care and why we are so deeply honored to work alongside him.

A Leader by the Numbers: Validated Global Impact

A surgeon’s reputation should be built on more than just words; it should be built on data. The ScholarGPS™ rankings, which analyze the productivity and impact of researchers worldwide, confirm Dr. Ceccaroni’s position as one of the most influential surgeons in his field.

His rankings are in the absolute highest tier:

  • Top 0.17% of Scholars for Endometriosis

  • Top 0.46% of Scholars for Laparoscopy

  • Top 0.82% of Scholars for Endometrial Cancer

These numbers paint a clear picture: Dr. Ceccaroni is not just a leader in Italy, but one of the most published and cited experts on endometriosis and minimally invasive surgery in the world.

The Birth of a New Field: Neurogynecology

What makes a surgeon a true pioneer? It is the ability to see the human body in a new way.

Dr. Ceccaroni’s revolutionary insight was to see endometriosis not just as a gynecologic disease, but as a neurologic one. As he has noted, his passion for neuroanatomy—the “alphabet of surgery”—allowed him to view the pelvis as a delicate network of “electric cables” (nerves) that control our lives, functions, and emotions.

He was one of the first to describe endometriosis as an “onco-mimetic disease”—a disease that acts like cancer, “infiltrating and disrupting the pelvic tissues as a big sea of lava.”

This profound understanding led to the birth of a new field: Neurogynecology. This is the science of how diseases like endometriosis interact with, invade, and disrupt the pelvic nerves, and more importantly, how to fix it.

The Surgical Revolution: The “Negrar Method”

A new mindset must be paired with a new technique. This is Dr. Ceccaroni’s legacy. He accepted the challenge of this “sea of lava” and developed a revolutionary nerve-sparing surgical approach, now famously known as the “Negrar Method.”

Published in leading journals like the one found on PubMed, this is not just a simple laparoscopy. It is a highly precise, anatomy-based dissection that redefines surgical success:

  1. It meticulously removes 100% of the deep infiltrating endometriosis.

  2. It simultaneously identifies, isolates, and preserves the vital pelvic nerves.

While older surgical approaches could leave patients with devastating, lifelong complications like bladder, bowel, or sexual dysfunction, Dr. Ceccaroni’s method proved that it was possible to remove the disease and preserve the patient’s quality of life. This is now the gold standard that all other expert excision surgeons strive to meet.

The ESSI Collaboration: A Meeting of Minds

It is this shared philosophy—this relentless commitment to innovation and patient-centric care—that makes Dr. Ceccaroni such a vital part of the ESSI team. We are a collective of surgeons who believe in pushing boundaries and sharing knowledge.

The perfect example of this synergy is the AdenoDue Procedure, a dual-surgical technique to treat both adenomyosis and endometriosis in a single minimally invasive operation.

Our founder, Dr. Andrea Vidali, shared his thoughts on this collaboration:

“Marcello’s AAGL ‘Original Innovator’ award was so deeply deserved. He is a ‘rebel’ in the best sense of the word—he saw the injustice of patients suffering from nerve damage after surgery, and he had the anatomical genius to create a revolutionary new solution. He is a teacher, a leader, and a force of nature. His partnership at ESSI is a daily reminder of our shared mission: to never stop innovating for our patients.”

– Dr. Andrea Vidali, Founder of ESSI

World-Class Care, Accessible Globally

ESSI is a global collective of the world’s most elite surgeons, united by a single mission. We are beyond honored to have Dr. Marcello Ceccaroni as a core member of our team, sharing his wisdom and pioneering techniques.

People Also Ask

1. Who is Dr. Marcello Ceccaroni? Dr. Marcello Ceccaroni is a world-renowned Italian endometriosis surgeon, a pioneer in the field of neurogynecology, and the creator of the “Negrar Method” for nerve-sparing surgery. He is a key member and surgical partner of the ESSI global team.

2. What is the “Negrar Method” for endometriosis? The “Negrar Method” is an advanced surgical technique created by Dr. Ceccaroni. It focuses on meticulously excising deep infiltrating endometriosis while anatomically identifying and preserving the delicate pelvic nerves, thereby protecting bladder, bowel, and sexual function.

3. What is Neurogynecology? Neurogynecology is a new field, pioneered by Dr. Ceccaroni, that studies the complex relationship between the pelvic nerves and gynecologic diseases like endometriosis. It provides the anatomical foundation for modern nerve-sparing excision surgery.

4. Can I see an ESSI doctor in Europe? Yes. ESSI is a global organization. We are proud to partner with Dr. Marcello Ceccaroni, and patients can access his world-class care at his center in Salerno, Italy.

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